Evidence-Based Research Platform

The Science of Vagus Nerve Stimulation

A curated collection of peer-reviewed research, clinical evidence, and educational resources on vagus nerve stimulation.

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Featured Articles

Vagus Nerve Stimulation for Migraine: From Trigeminal Pathways to Clinical Evidence
Migraine15 min read

Vagus Nerve Stimulation for Migraine: From Trigeminal Pathways to Clinical Evidence

A comprehensive review of vagus nerve stimulation for migraine — covering clinical trial evidence, mechanisms involving trigeminal-vagal pathways and cortical spreading depression, and comparison with current therapies.

Vagus Nerve Stimulation for PTSD: From Fear Circuits to Clinical Breakthroughs
PTSD16 min read

Vagus Nerve Stimulation for PTSD: From Fear Circuits to Clinical Breakthroughs

An in-depth review of how vagus nerve stimulation targets the neural circuits underlying PTSD — from preclinical breakthroughs in fear extinction to landmark clinical trials showing complete loss of diagnosis.

Vagus Nerve Stimulation for Stroke Rehabilitation: Targeted Plasticity Therapy
Stroke15 min read

Vagus Nerve Stimulation for Stroke Rehabilitation: Targeted Plasticity Therapy

How VNS paired with rehabilitation drives targeted neuroplasticity to restore motor function after stroke — from the preclinical science at UT Dallas to FDA approval and long-term outcomes.

818
Human Studies
22,966
Participants reported in primary studies
47+
Clinical Populations
43+
Years of Research

Participant counts are summed across primary-study reports; people may appear in more than one paper. Reviews and guidelines are excluded; missing counts are omitted.

Research cited from

  • UT Dallas
  • University of Leeds
  • Harvard / Mass General
  • University of Glasgow
  • MUSC
  • University of Amsterdam
  • McGill University
  • Emory University
  • NYU
  • University of Gothenburg
  • Feinstein Institutes

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Research Areas

AddictionAnxietyAthletic RecoveryCognitive FunctionDepressionDysautonomiaEpilepsyFibromyalgiaFoundationGut HealthHeart FailureHeart HealthInflammationInflammatory Bowel DiseaseIrritable Bowel SyndromeLong COVIDMetabolic HealthMigraineNeuroplasticityPTSDPainParkinson's DiseaseRheumatoid ArthritisSafetySleepStrokeTinnitus

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Every human study we hold for a condition, graded and summarised on one page — 47 conditions in all.

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